What's Tadalafil?

1.what's tadalafil used for?
Tadalafil (Cialis) is used for the treatment of men who have benign prostatic hyperplasia (BPH) or erectile dysfunction (ED), or both conditions. Tadalafil (Adcirca) is used to treat pulmonary arterial hypertension (PAH).


With BPH, the prostate gland is enlarged but isn’t cancerous. It can pinch or squeeze your urethra (the tube that carries urine from the kidneys out of the body). Symptoms of BPH include trouble urinating, painful urination, and a frequent or urgent need to urinate.


With ED, the penis doesn’t fill up with enough blood to harden and expand when a man is sexually excited. ED can also prevent a man from keeping an erection.


PAH is a rare but serious form of high blood pressure. It occurs in the pulmonary arteries, which are blood vessels in your lungs.


2.How Tadlafil works?
Tadalafil belongs to a class of drugs called phosphodiesterase type 5 (PDE5) inhibitors. A class of drugs is a group of medications that work in a similar way. These drugs are often used to treat similar conditions.


Tadalafil may help relax the muscle in your prostate and bladder. This could help improve your BPH symptoms.


To improve ED symptoms, tadalafil helps increase blood flow to the penis. This can help you get and keep an erection. For tadalafil to help you have an erection, you need to be sexually aroused.


For PAH, tadalafil works to improve your ability to exercise by relaxing blood vessels in your lungs. This increases blood flow.


3.What's the difference between Tadalafil and Sildenafil?
Tadalafil and Sildenafil are marketed as Revatio and Adcirca for pulmonary arterial hypertension.


Tadalafil and Sildenafil received approval for treatment of pulmonary arterial hypertension (PAH).Tadalafil also comes as Cialis which is approved to treat the signs and symptoms of benign prostatic hyperplasia (BPH), a condition in which the prostate gland becomes enlarged. The use of Sildenafil and Tadalafil are contraindicated in patients who are using any form of organic nitrate, either regularly or intermittently.



And Tadalafil (generic Cialis) has an advantage over Sildenafil in that it lasts a lot longer – up to 36 hours (compared with 4-5 hours for Sildenafil). Some men prefer this as it allows for more spontaneity.




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Reference

1. Richards, Rhonda (September 17, 1991). "ICOS At A Crest On Roller Coaster". USA Today. p. 3B.
2. "Tadalafil". Drugs.com. Retrieved February 23, 2018.
3. Revill, Jo (February 2, 2003). "Drugs giant says its new pill will pack more punch than rival Viagra". The Observer. Retrieved 2007-04-06.
4. "FDA approves Cialis to treat benign prostatic hyperplasia". U.S. Food and Drug Administration (FDA). 2011-10-06. Archived from the original on 2017-01-18.







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