<

Top 5 Benefits Of Taking Pyrroloquinoline Quinone (PQQ) You Must Know

 

 

What is pyrroloquinoline quinone disodium salt?

Pyrroloquinoline Quinone disodium salt (PQQ), also called methoxatin, is a redox cofactor. Pyrroloquinoline Quinone disodium salt or PQQ is a recently discovered vitamin-like compound that is commonly found in plant foods. It is found in soil and foods such as kiwifruit, as well as human breast milk. Enzymes containing PQQ are called quinoproteins. Glucose dehydrogenase, one of the quinoproteins, is used as a glucose sensor. PQQ stimulates growth in bacteria.

 

It was first discovered as a cofactor for bacteria that is similar to how B Vitamins effect humans. PQQ has antioxidant and B-vitamin-like activity, with a wide range of benefits for the brain and body. It promotes cognitive health and memory by combatting mitochondrial dysfunction and protecting neurons from oxidative damage. It supports energy metabolism and healthy aging.

 

Pyrroloquinoline quinone disodium salt benefits

Pyrroloquinoline quinone — or PQQ — has recently gained a lot of attention in the health and wellness sphere. The interest in Pyrroloquinoline Quinone has increased considerably during the last few years as this compound has been linked with several benefits. Here, we look at its most important Pyrroloquinoline Quinone (PQQ) benefits.

 

  • Improves Optimal Mitochondrial Function

 

Mitochondria are the energy producers in our cells and they play an important role in our overall health. Mitochondrial dysfunction has been the root cause of most neurodegenerative diseases such as Alzheimer’s, multiple sclerosis, Parkinson’s syndrome, and cancer progression.

 

PQQ has diverse benefits for mitochondrial function having been shown to diminish mitochondrial oxidative stress as well as stimulate mitochondrial biogenesis. Taking PQQ Alzheimer’s supplement will fire up the generation of mitochondria. Over the years, dietary supplements and pharmaceutical drugs have proved to be promising for boosting the density and efficacy of this cell organelle. One of the groundbreaking inventions was the discovery of pyrroloquinoline quinone.

 

PQQ has diverse benefits for mitochondrial function. It has been shown to attenuate mitochondrial oxidative stress as well as stimulate mitochondrial biogenesis. It promotes cognitive health and memory by combatting mitochondrial dysfunction and protecting neurons from oxidative damage. Besides, it alleviates oxidative stress within the cellular tissues. Therefore, PQQ can be a silent anti-aging compound, which improves cognition and memory, while reversing neuronal disorders associated with senescence.

 

  • Supports Nerve Growth Factors

 

Nerve Growth Factor, or NGF, refers to a large group of protein-like molecules which are key in the maintenance and development of nerve cells. PQQ enhances the biosynthesis of nerve growth factor (NGF), a key protein involved in the growth and survival of neurons.

 

PQQ is known to influence multiple cellular pathways, which enhances the production of nerve growth factor (NGF). When PQQ interacts with the cellular pathways, it always leaves a positive impact on the nerve growth factors (NGF) by enhancing their progression. It ensures the survival and development of the neuronal cells. Consequently, there’s protection of the neurons and the production of nerves in the cranial tissues. Clinicians have been linking NGF dysregulation with Alzheimer’s disease. PQQ supplements are often prescribed to aid the treatment of age-related conditions.

 

  • Prevents Oxidative Stress

 

Oxidative stress occurs when there is a buildup of oxidative radicals in our bodies. Oxidative stress is responsible for major chronic illnesses such as neurodegenerative diseases and some carcinomas.

 

PQQ binds to proteins hence inhibits oxidation in the cells and decreases the levels of IL-6 and C-Reactive Protein, which are contributing markers of inflammation. PQQ protects cells in the body from oxidative damage and supports the metabolism of energy and healthy aging. It is also able to get rid of free radicals in the body.

Pyrroloquinoline quinone disodium It is also considered a novel cofactor with antioxidant and B vitamin-like activity.

 

In the current situation in the world, negative news due to the COVID 19 is coming in every time. Pyrroloquinoline quinone coronavirus fight can be utilized. This exciting supplement will enhance your immunity as well offer sleep aid to relieve you stress.

 

  • Helps Neuroprotection

 

Pyrroloquinoline quinone disodium salt improves higher brain function, cognition, memory, and attention. Efficiency in the mitochondrial functions guarantees a healthy lifestyle that’s free from neurodegenerative diseases.

 

PQQ intake has been linked with reduced stress, which in turn, leads to enhanced cognitive function and improvements to memory. Research studies have been conducted to study how PQQ affects memory. In a clinical study involving 41 elderly subjects, the scholars established that PQQ could boost cognition, prevent memory loss, and improve attention.

 

  • Other benefits of pyrroloquinoline quinone disodium salt

 

Over and above the aforementioned benefits, PQQ also offers some other benefits the research on which is currently underway. For instance, preliminary research has proven that PQQ intake also leads to improved fertility. Here is some other benefits as follow:

 

Preventing obesity

Improves immune system

Improves fertility

Promotes cognitive functioning and memory

Helps fight fatigue

 

Is pyrroloquinoline quinone disodium salt (PQQ) safe?

When obtaining PQQ from food sources no side effects are expected unless one is allergic to the certain food.

 

Adverse Pyrroloquinoline quinone side effects are quite sporadic especially if you stick to the standard 20-40mg daily dose with short-term use. However, in rare occurrences, some possible pyrroloquinoline quinone side effects can occur due to taking overdoses. These side effects include headaches, fatigue, drowsiness, hypersensitivity and insomnia. Humans ought not to exceed one year of consistent usage.

 

Well, you should be blissful that the compound has no adverse side effects. However, ensure to embrace a low dosage as a key Pyrroloquinoline quinone safety measure.

 

Where you can buy pyrroloquinoline quinone disodium salt (PQQ) in Bulk?

With people becoming more and more aware of the benefits of pyrroloquinoline quinone disodium salt (PQQ) , the demand for pyrroloquinoline quinone disodium salt (PQQ) supplements has increased greatly in the market. This has led to manufacturing companies vying with each other to produce high-quality supplements to grab share in the market. If you are a health supplements manufacturer planning to foray into the pyrroloquinoline quinone disodium salt (PQQ) supplements market, you must ensure that you are getting the highest-quality pyrroloquinoline quinone disodium salt (PQQ) powder. Sourcing good-quality material is the first step in ensuring the success of any business.

 

If you are looking for a place to buy pyrroloquinoline quinone disodium salt (PQQ) powder in bulk, the one company you can blindly trust for sourcing raw material is Cofttek. The company, owing to its strong research team and dedicated sales department, has established a worldwide presence in only a short amount of time — it has clients and partners around the world. The pyrroloquinoline quinone disodium salt (PQQ) produced by the company comes in big batches of 25 kgs and is sourced from highest-quality ingredients, thereby ensuring that the supplements produced from it can be trusted for quality and efficacy. If you want to buy pyrroloquinoline quinone disodium salt (PQQ) in bulk, the only place to shop is cofttek.com.

 

 

 

 

 

 

REFERENCES

 

[1]. Genotoxicity of pyrroloquinoline quinone (PQQ) disodium salt (BioPQQ).

Nakano M, Suzuki H, Imamura T, Lau A, Lynch B.Regul Toxicol Pharmacol. 2013 Nov;67(2):189-97. doi: 10.1016/j.yrtph.2013.07.007. Epub 2013 Jul 25.PMID: 23891671

  1. Acute and subchronic toxicity studies of  pyrroloquinoline  quinone (PQQ) disodium salt (BioPQQ) in rats. Nakano M, Takahashi H, Koura S, Chung C, Tafazoli S, Roberts A.Regul Toxicol Pharmacol. 2014 Oct;70(1):107-21. doi: 10.1016/j.yrtph.2014.06.024. Epub 2014 Jul 1.PMID: 24995591

  2. Crystal structure and characterization of  pyrroloquinoline  quinone  disodiumtrihydrate. Ikemoto K, Sakamoto H, Nakano M.Chem Cent J. 2012 Jun 19;6(1):57. doi: 10.1186/1752-153X-6-57.PMID: 22713213 

  3. Effects of Antioxidant Supplements (BioPQQ™) on Cerebral Blood Flow and Oxygen Metabolism in the Prefrontal Cortex. Nakano M, Murayama Y, Hu L, Ikemoto K, Uetake T, Sakatani K.Adv Exp Med Biol. 2016;923:215-222. doi: 10.1007/978-3-319-38810-6_29.PMID: 27526146 

  4. Synthesis and crystal structure of pyrroloquinoline quinol (PQQH2) and pyrroloquinoline quinone (PQQ). Ikemoto K, Mori S, Mukai K.Acta Crystallogr B Struct Sci Cryst Eng Mater. 2017 Jun 1;73(Pt 3):489-497. doi: 10.1107/S2052520617002281. Epub 2017 Jun 1.PMID: 28572558